Human brain organoids flourish in emptied mouse cortex
thetransmitter.org
Human brain organoids transplanted into mice with an engineered absence of cerebral cortex integrate into the host's nervous system, forming functional circuits that support electrical activity. This xenocortical model provides a novel platform to study human brain development and neurodevelopmental disorders like autism and epilepsy, as well as test potential treatments. The approach overcomes limitations of traditional models by allowing human neurons to mature and form complex circuits in a living system.
All articles from 5 October 2026. Summaries are AI-generated and may contain errors; the linked article is the authority.