Neural signaling protein could be therapeutic target for autism-linked gene deletion

A study by University of Illinois Urbana-Champaign researchers suggests that the neural signaling protein PSD-95 could be a therapeutic target for neurological disorders caused by deletions of the autism-linked gene MEF2C. Mice with MEF2C haploinsufficiency exhibited cognitive impairments and seizures, which were alleviated by reducing PSD-95 levels. The findings indicate that inhibiting PSD-95 may help restore cognitive function and reduce seizures in individuals with MEF2C haploinsufficiency and related disorders.

Read at University of Illinois Urbana-Champaign

All articles from 27 October 2026. Summaries are AI-generated and may contain errors; the linked article is the authority.