Plasma Levels of Methylphenidate Track Clinical Response in Youth with ADHD Better Than Urine Tests

Bioengineer.org

Plasma levels of methylphenidate correlate more closely with clinical outcomes in youth with ADHD compared to urine levels, making plasma-based therapeutic drug monitoring more effective for guiding treatment. The study found that plasma methylphenidate concentrations showed stronger associations with symptom assessments than urine concentrations, highlighting the importance of plasma testing for accurate dosing and monitoring. Urine tests, while useful, do not reliably reflect the drug's presence in the body in the same way as plasma measurements.

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All articles from 29 October 2026. Summaries are AI-generated and may contain errors; the linked article is the authority.